Neue Publikation

12. Mai 2021, von Cen Zeng

Shab's protein engineering experiments in our lab helped to dissect the evolutionary path that enabled toad-feeding frogs to become resistant to their prey's toxins while maintaining highly active Na, K-ATPases and withstanding the homogenizing force of gene conversion.

Mohammadi S., Yang L., Harpak A., Herrera-Álvarez S., Rodríguez-Ordoñez M., Peng J., Zhang K., Storz J.F., Dobler S., Crawford A.J., Andolfatto P. (2021) Concerted evolution reveals co-adapted amino acid substitutions in Na+K+-ATPase of frogs that prey on toxic toads. Current Biology