Welcome back, Shab!

6 January 2020, by Cen Zeng

Dr. Shabnam Mohammadi just arrived for the forth time in our lab, founed for two years by her own NIH fellowship. You can find her most of the time in the cell culture room producing Na,K-ATPase constructs with various degrees of resistance to cardiac glycosides.

Latest articles

Photo: Marlena Herbertz

29.03.2022|molevolbio

New insights into an insect Na,K-ATPase

The Na,K-ATPase is a vital ion transporter and ubiquitously expressed in all animal cells. The enzyme is composed of two functionally diverse subunits in invertebrates, an α and a β-subunit. The ion transport can be inhibited by cardiac glycosides with harmful or even lethal effects on the organism...

12.05.2021|molevolbio

New Publication in Current Biology

Shab's protein engineering experiments in our lab helped to dissect the evolutionary path that enabled toad-feeding frogs to become resistant to their prey's toxins while maintaining highly active Na, K-ATPases and withstanding the homogenizing force of gene conversion.

Mohammadi S., Yang L., Harpak...