Abschlussarbeiten

2021

Hilke Duin Symbiotic plasmid (pNGR234a) copy number in the broad host range bacterium Sinorhizobium fredii NGR234 depends on quorum sensing and phenotypic heterogeneity

Mirja Gudzuhn Stenotrophomonas maltophilia biofilms: Molecular keys to multicellularity, phenotypic heterogeneity and persistence on surfaces

2020

Andrea Schorn How to bark up the right tree – Novel metagenomic laccase-like multicopper oxidases from the European spruce bark beetle Ips typographus (E-Dissertation)

Katharina Saß Analysis of the microbial community and functionality along the Kermadec Arc and its surroundings

Nicole M. Adam Microbial hydrogen oxidation in deep-sea hydrothermal vents 

Pablo Pérez-García Enzyme promiscuity at the origin of metallo-β-lactamases and within the α/β-hydrolase superfamily (E-Dissertation)

Katrin Petersen Quorum sensing-dependent expression of small proteins and structural analysis of new class of quorum quenching enzymes (E-Dissertation)

2019

Tanja Vanessa Heyer Development of a Whole Cell Fermentation Process for Glycosylation of Small Molecule Flavonoids (E-Dissertation)

Constantin Ruprecht Engineering Escherichia coli to glycosylate polyphenols

2018

Dominik Danso Function and Global Distribution of Polyethylene Terephthalate (PET)-Degrading Bacteria and Enzymes in Marine and Terrestrial Metagenomes (E-Dissertation)

Birhanu Kinfu Function-based searches for selected phosphotransferases and establishing in vitro transcription platform for cell-free metagenomics (E-Dissertation)

Simone Wegen Characterization of Candidatus Nitrotoga and its Competitiveness in Co-Culture with Nitrospira

2017

Jennifer Hüpeden Taxonomic and functional diversity of nitrifyingbiofilm communities in biofilters of different recirculatin aquaculture systems

2016

Jessica Grote Deciphering regulatory mechanisms involved in phenotypic heterogeneity of the autoinducer synthase genes traI and ngrI in Sinorhizobium fredii NGR234 using single cell technologies and RNA-seq (E-Dissertation)

Simon Güllert Deep metagenome and metatranscriptome analyses of plant biomassdegrading microbial communities to improve lignocellulose conversion (E-Dissertation)

Frederike S. Haack Genome, mutational and RNA-seq analyses of Janthinobacterium and Duganella strains reveal the presence of a single α-hydroxyketone-like quorum sensing system involved in bacterial-fungal interactions (E-Dissertation)

Moritz Hansen H₂ oxidation as a novel trait among the sulfur-oxidizing Thiomicrospira lineage

Ebrahim Mama Abda Identifying molecular keys regulating phenotypic heterogeneity of Stenotrophomonas maltophilia K279a β-lactamase bla_L1 and bla_L2 gene expression (E-Dissertation)

2015

Hanaë A. Henke The Staphylococcus epidermidis biofilm matrix: functional components, molecular interactions and targeted enzymatic disruption (E-Dissertation)

Janine Maimanakos Vorkommen, Verbreitung und biochemische Charakterisierung bakterieller Arylmalonat- Decarboxylasen (E-Dissertation)

Gao Rong Genome-wide RNA-seq analysis of quorum sensing-dependent regulons in the plant-associated Bukholderia glumae strain PG1 (E-Dissertation)

Nicolas Rychlik Hydrogenases from a hydrothermal deep-sea vent metagenome and the development of a novel activity-based screen to identify H₂ uptake active enzymes from metagenomic libraries

Christian Utpatel RNA-seq based identification and biochemical characterization of the Pseudomonas Aeruginosa LasR and quorum sensing anti-activator PA2226 (E-Dissertation)

2014

Stefanie Böhnke A novel function-based screen for detecting RubisCO active clones from metagenomic libraries: elucidating the role of RubisCO associated enzymes (E-Dissertation)

Julia Jürgensen Identification of an unusual GTase from a non-cultivated microorganism and the construction of an improved E. coli strain harboring the rpoD gene from C. cellulolyticum for metagenome searches (E-Dissertation)

Boris Nowka Activity and ecophysiology of nitrite-oxidizing bacteria in natural and engineered habitats  (E-Dissertation)

2013

Claudia K. Hornung Violacein-producing Janthinobacterium sp. HH01 – Genome analysis revealed a novel α-hydroxyketone-sensing reporter-strain (E-Dissertation)

Ines Krohn-Molt Metagenomische und physiologische Analysen der Interaktion zwischen Mikroalgen und Bakterien in Photobioreaktoren  (E-Dissertation)

Ulrich Rabausch Metagenome derived carbohydrate active enzymes for directed modification of polyphenols  (E-Dissertation)

2012

Patrick Bijtenhoorn Characterization of novel metagenomic quorum quenching enzymes attenuating Pseudomonas aeruginosa motility, biofilm formation and virulence (E-Dissertation)

Jennifer Chow Biochemical and Structural Characterization Of Three Thermostable and Metagenome-Derived Lipolytic Enzymes (E-Dissertation)

Sandra Off Nitrospira Schlüsselorganismus der Nitritoxidation in gemäßigten und extremen Lebensräumen  (E-Dissertation)

Arkadius Ozimek Durchmusterung von Metagenombibliotheken nach biotechnologisch relevanten Phytasen und Entwicklung eines EGFP-basierten Nachweisverfahrens 

2011

Nele Ilmberger Metagenomic cellulases from Bacteria linking IL-tolerance, halotolerance and thermostability (E-Dissertation)

Sabine Keuter Characterization of nitrifying bacteria in marine recirculation aquaculture systems with regard to process optimization (E-Dissertation)

Dagmar Krysciak The complete genome sequence of Rhizobium sp. NGR234 reveals a surprisingly large number of quorum quenching associated genes (E-Dissertation)

2009

Julia Pottkämper Cellulase-Aktivitäten nicht-kultivierter Mikroorganismen in ionischen Flüssigkeiten

Christina Schipper Quorum Quenching und Anti-Biofilm Strategien aus Metagenom - Isolierung und Charakterisierung Quorum Sensing inhibierender Proteine aus Genbanken direkt isolierter Umwelt-DNA (E-Dissertation)

2006

Christian Elend Metagenombasierte Isolierung und biochemische Charakterisierung neuartiger stereospezifischer Lipasen für biokatalytische Anwendungen (E-Dissertation)

Sonja Voget Metagenomanalyse eines hydrolytischen Konsortiums: Identifizierung und biochemische Charakterisierung von Polysaccharid-abbauenden Biokatalysatoren aus nicht kultivierten Mikroorganismen (E-Dissertation)

2004

Christel Schmeißer (Vollstedt) Metagenomanalyse eines Multispezies-Biofilms: Biochemische Charakterisierung und Kristallisierung der ersten multimeren Esterase aus einem bisher nicht kultivierten Mikroorganismus (E-Dissertation)

Christian Stöckigt Konstruktion und Durchmusterung von Metagenombanken: Identifizierung und Charakterisierung von neuartigen amylolytischen Enzymen

2002

Elke Heinz Molekulare Analyse des Biotin-regulatorischen Netzwerks in Sinorhizobium meliloti durch Proteomanalyse, Expressionsstudien und Mutagenesen (E-Dissertation)

2001

Plamena Entcheva Umwelt-Genomik als Quelle für die Isolierung von neuen Operons und Genclustern aus mikrobiellen Konsortien (E-Dissertation)