Publications
Publications and Publications in press
2024
Zannoni R, Keil J, Ponseti J, Stirn AV, Holtfrerich SKC, Diekhof EK (2024). Modulation of the attentional response to baby schema by testosterone in pedohebephilic men and its relation to the nurturing system. Scientific Reports volume 14: 16385
Diekhof EK, Deinert L, Keller JK, Degner J (2024) The COVID-19 pandemic and changes in social behavior: Protective face masks reduce deliberate social distancing preferences while leaving automatic avoidance behavior unaffected. Cognitive Research: Principles and Implications 9: 2
Holtfrerich SKC, Diekhof EK (2024) Selective attention towards infants in nulliparous women across the menstrual cycle. Hormones & Behavior
Keller JK, Kusari A, Czok S, Simgen B, Steinicke F, Diekhof EK (2024). ACHOO - Bless you! Sense of Presence can provoke Proactive Mucosal Immune Responses in Human-Agent Interactions. IEEE VR 2024
Janet R, Kohne S, Diekhof EK (submitted) Testosterone and cortisol affect male risk-taking from adolescence into early adulthood in the Balloon Analogue Risk Task. Andrology
Keller JK, Diekhof EK (2024). Influence of female sex steroid hormones on proactive behavioral and physiological immune parameters. Reproductive Biology
2023
Keller JK, Dulovic A, Gruber J, Griesbaum J, Schneiderhan-Marra N, Wülfing C, Kruse J, Hartmann A, Diekhof EK (2023). SARS-CoV-2 specific sIgA in saliva increases after disease-related video stimulation. Scientific Reports 13: 22631
2022
Keller JK, Wülfing C, Wahl J, Diekhof, EK (2022). Disease-related disgust promotes antibody release in human saliva. Brain Behav. Immun. - Health 24, 100489.
Kohne S, Diekhof EK (2022). Testosterone and estradiol affect adolescent reinforcement learning. PeerJ, 10: e12653.
2021
Kohne S, Reimers L, Müller M, Diekhof EK (2021). Daytime and season do not affect reinforcement learning capacity in a response time adjustment task. Chronobiology International, Vol. 38, No. 12: 1738-1744.
Diekhof EK, Geana A, Ohm F, Doll BB, Frank MJ (2021). The Straw That Broke the Camel's Back: Natural Variations in 17β-Estradiol and COMT-Val158Met Genotype Interact in the Modulation of Model-Free and Model-Based Control. Frontiers of Behavioral Neuroscience, 8;15:658769. Part of Research Topic ""Sex Hormone Fluctuations Across the Female Lifespan: Mechanisms of Action on Brain Structure, Function, and Behavior"
Diekhof EK, Richter A, Brodmann K, Gruber O (2021). Dopamine multilocus genetic profiles predict sex differences in reactivity of the human reward system. Brain Structure and Function, 226: 1099–1114.
2020
Holtfrerich SKC, Knipper S, Purwins J, Castens J, Beyer B, Schlomm T, Diekhof EK (2020). The impact of long-term androgen deprivation therapy on cognitive function and socioeconomic decision making in prostate cancer patients. Psycho-Oncology, 29 (8): 1338-1346.
Diekhof EK, Korf S, Ott F, Schädlich C, Holtfrerich SKC (2020). Avoidance Learning Across the Menstrual Cycle: A Conceptual Replication. Frontiers in Endocrinology, 11: 231. Part of the Research Topic “Recent Progress and Perspectives in Neurosteroid Research”
2019
Reimers L, Kappo E, Stadler L, Yaqubi M, Diekhof EK (2019). Endogenous testosterone correlates with parochial altruism depending on decision strategy in relation to costly punishment. PeerJ, in press
Richter A, Krämer B, Diekhof EK, Gruber O (2019). Resilience to adversity is associated with increased activity and connectivity in the VTA and hippocampus. Neuroimage Clin. Vol. 23: 101920[PDED1
Schwarz KA, Sprenger C, Hidalgo P, Pfister R, Diekhof EK, Büchel C (2019). How Stereotypes Affect Pain. Scientific Reports 9, Article number: 8626
Diekhof EK, Reimers L, Holtfrerich SKC (2019). Hormonal Modulation of Reinforcement Learning and Reward-Related Processes – A Role for 17ß-Estradiol, Progesterone and Testosterone, in: Schultheiss, O., Mehta, P. (Eds.), Routledge International Handbook of Social Neuroendocrinology. Routledge, London and New York, 420–441.
2018
Sommer T, Richter K, Singer F, Derntl B, Rune GM, Diekhof EK, Bayer J (2018). Effects of the experimental administration of oral estrogen on prefrontal functions in healthy young women. Psychopharmacology. Oct. 2018: 1-13.
Holtfrerich SKC, Pfister R, El Gammal AT, Bellon E, Diekhof EK (2018). Endogenous testosterone and exogenous oxytocin influence the response to baby schema in the female brain. Scientific Reports. 8:7672, 1–10. https://doi.org/10.1038/s41598-018-26020-4
Diekhof EK (2018).Estradiol and the reward system in humans. Current Opinion in Behavioral Sciences, 23: 58-64. Part of the Research Topic “Gender Differences in the Brain”
Jakob K, Ehrentreich H, Holtfrerich SKC, Reimers L, Diekhof EK (2018). DAT1-Genotype and Menstrual Cycle, but Not Hormonal Contraception, Modulate Reinforcement Learning: Preliminary Evidence. Frontiers in Endocrinology, 9: 60. Part of the Research Topic “Steroids and the Brain”
2017
Diekhof EK, Kraft S (2017). The association between endogenous testosterone level and behavioral flexibility in young men - Evidence from stimulus-outcome reversal learning. Hormones and Behavior, 89:193-200
Reimers L, Büchel C, Diekhof EK (2017). Neural substrates of male parochial altruism are modulated by testosterone and behavioral strategy. NeuroImage. 156: 265-276
2016
Diekhof EK, Ratnayake M (2016). Menstrual cycle phase modulates reward sensitivity and performance monitoring in young women: Preliminary fMRI evidence. Neuropsychologia. 84:70-80. Epub 2015 Oct 22
Holtfrerich SKC, Schwarz KA, Sprenger C, Reimers L, Diekhof EK (2016). Endogenous Testosterone and Exogenous Oxytocin Modulate Attention Processing of Infant Faces. PLoS One. 2016 Nov 18;11(11):e0166617.
Trost S, Diekhof EK, Mohr H, Vieker H, Krämer B, Wolf C, Keil M, Dechent P, Binder EB, Gruber O (2016). Investigating the Impact of a Genome-Wide Supported Bipolar Risk Variant of MAD1L1 on the Human Reward System. Neuropsychopharmacology. [Epub ahead of print]
Zilles D, Lewandowski M, Vieker H, Henseler I, Diekhof E, Melcher T, Keil M, Gruber O (2016). Gender Differences in Verbal and Visuospatial Working Memory Performance and Networks. Neuropsychobiology. 73: 52-63. Epub 2016 Feb 10.
2015
Diekhof EK (2015). Be quick about it. Endogenous estradiol level, menstrual cycle phase and trait impulsiveness predict impulsive choice in the context of reward acquisition. Hormones and Behavior, 74: 186-93
Reimers L, Diekhof EK (2015). Testosterone is associated with cooperation during intergroup competition by enhancing parochial altruism. Front. Neurosci., 9: 183 Free PMC Article
Chahine G, Diekhof EK, Tinnermann A, Gruber O. (2015). On the role of the anterior prefrontal cortex in cognitive 'branching': An fMRI study. Neuropsychologia, 77: 421-9
Wolf C, Mohr H, Diekhof EK, Vieker H, Goya-Maldonado R, Trost S, Krämer B, Keil M, Binder EB, Gruber O (2015). CREB1 Genotype Modulates Adaptive Reward-Based Decisions in Humans. Cerebral Cortex, pii: bhv104. [Epub ahead of print]
Richter A, Petrovic A, Diekhof EK, TroHyst S, Wolter S, Gruber O. (2015). Hyperresponsivity and impaired prefrontal control of the mesolimbic reward system in schizophrenia. Journal of Psychiatry Research, 71: 8-15
Goya-Maldonado R, Weber K, Trost S, Diekhof E, Keil M, Dechent P, Gruber O (2015). Dissociating pathomechanisms of depression with fMRI: bottom-up or top-down dysfuntions of the reward system. European Archives of Psychiatry and Clinical Neuroscience, 265(1):57-66
2014
Diekhof EK, Wittmer S, Reimers L (2014). Does competition really bring out the worst? Testosterone, social distance and inter-male competition shape parochial altruism in human males. PLoS One, 9: e98977
Reimers L, Büchel C, Diekhof EK (2014). How to be patient. The ability to wait for a reward depends on menstrual cycle phase and feedback-related activity. Frontiers in Neuroscience, 8: 401
Diekhof EK, Gruber O (2014). Untersuchung funktioneller und effektiver Konnektivität mit fMRT. In: Gruber, O., Falkai, P. (Eds.): Systemische Neurowissenschaften in der Psychiatrie, Kohlhammer-Verlag
Trost S, Diekhof EK, Zvonik K, Lewandowski M, Usher J, Keil M, Zilles D, Falkai P, Dechent P, Gruber O (2014). Disturbed anterior prefrontal control of the dopaminergic reward system and increased impulsivity in bipolar disorder. Neuropsychopharmacology, 39: 1914-1923
2012
Diekhof EK, Keil M, Obst KU, Henseler I, Dechent P, Falkai P, Gruber O (2012). A functional neuroimaging study assessing gender differences in the neural mechanisms underlying the ability to resist impulsive desires. Brain Research, 1473: 63 -77
Diekhof EK, Nerenberg L, Falkai P, Dechent P, Baudewig J, Gruber O (2012). Impulsive personality and the ability to resist immediate reward: An fMRI study examining interindividual differences in the neural mechanisms underlying self-control. Human Brain Mapping, 33: 2768-2784
Diekhof EK, Kaps L, Falkai P, Gruber O (2012). The role of the human ventral striatum and the medial orbitofrontal cortex in the representation of reward magnitude - An activation likelihood estimation meta-analysis of neuroimaging studies of passive reward expectancy and outcome processing. Neuropsychologia, 50(7):1252-66
2011
Diekhof EK, Kipshagen HE, Falkai P, Dechent P, Baudewig J, Gruber O (2011). The power of imagination--how anticipatory mental imagery alters perceptual processing of fearful facial expressions. Neuroimage, 54(2): 1703-14
Diekhof EK, Geier K, Falkai P, Gruber O (2011). Fear is only as deep as the mind allows: a coordinate-based meta-analysis of neuroimaging studies on the regulation of negative affect. Neuroimage, 58(1): 275-85
Diekhof EK, Falkai P, Gruber O (2011). The orbitofrontal cortex and its role in the assignment of behavioural significance. Neuropsychologia, 49(5): 984-91
2010
Diekhof EK, Gruber O (2010). When desire collides with reason: functional interactions between anteroventral prefrontal cortex and nucleus accumbens underlie the human ability to resist impulsive desires. Journal of Neuroscience, 30(4): 1488-1493
Gruber O, Diekhof EK, Kirchenbauer L, Goschke T (2010). A neural system for evaluating the behavioural relevance of salient events outside the current focus of attention. Brain Research 10, 1351:212-21
2009
Diekhof EK, Falkai P, Gruber O (2009). Functional interactions guiding adaptive processing of behavioral significance. Human Brain Mapping, 30 (10): 3325-3331
Diekhof EK, Biedermann F, Ruebsamen R, Gruber O (2009). Top-down and bottom-up modulation of brain structures involved in auditory discrimination. Brain Research, 1297: 118-123
Gruber O, Melcher T, Diekhof EK, Karch S, Falkai P, Goschke T (2009). Brain mechanisms associated with background monitoring of the environment for potentially significant sensory events. Brain and Cognition, 69: 559-64
2008
Diekhof EK, Falkai P, Gruber O (2008). Functional neuroimaging of reward processing and decision-making: A review of aberrant motivational and affective processing in addiction and mood disorders. Brain Research Reviews, 59: 164-184
Diekhof EK, Gruber O (2008). [Functional organisation of frontal cortex. Part 1: Elementary findings in systemic neuroscience]. Fortschritte der Neurologie Psychiatrie, 76(1):49-57
Gruber O, Diekhof EK, Falkai P (2008). [Functional organisation of frontal cortex]. Fortschitte der Neurologie Psychiatrie, 76(3):174-80