For full publication list please see link on the right or view Google Scholar profile
Radwan J, Babik W, Kaufman J, Lenz TL, Winternitz J (2020) Advances in the evolutionary understanding of MHC polymorphism. Trends in Genetics 36: 298-311.
Severe Covid-19 GWAS Group (2020) Genome-wide association study in severe Covid-19 with respiratory failure. New England Journal of Medicine 383:1522-1534.
Arora J, Pierini F, McLaren PJ, Carrington M, Fellay J, Lenz TL (2020) HLA heterozygote advantage against HIV-1 is driven by quantitative and qualitative differences in HLA allele-specific peptide presentation. Molecular Biology and Evolution 37: 639-650.
Chowell D, Krishna C, Pierini F, Makarov V, Rizvi NA, Kuo F, Riaz N, Lenz TL*, Chan TA* (2019) Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy. Nature Medicine 25: 1715-1720.
Arora J, McLaren PJ, Chaturvedi N, Carrington M, Fellay J, Lenz TL (2019) HIV peptidome-wide association study reveals patient-specific epitope repertoires associated with HIV control. PNAS 116: 944-949.
Pierini F, Lenz TL (2018) Divergent allele advantage at human MHC genes: signatures of past and ongoing selection. Molecular Biology and Evolution 35: 2145-2158.
Krause-Kyora B, Nutsua M, Böhme L, Pierini F, Pedersen DD, Kornell S-C, Drichel D, Bonazzi M, Möbus L, Tarp P, Susat J, Bosse E, Willburger B, Schmidt AH, Sauter J, Franke A, Wittig M, Calibe A, Nothnagel M, Schreiber S, Boldsen J*, Lenz TL*, Nebel A* (2018) Ancient DNA study reveals HLA susceptibility loci for leprosy in medieval Europeans. Nature Communications 9: 1569.
Lenz TL*, Deutsch AJ*, Han B, Hu XY, Okada Y, Eyre S, [28 coauthors], de Bakker PIW, Raychaudhuri S (2015) Widespread non-additive and interaction effects within the HLA modulate the risk of autoimmune diseases. Nature Genetics 47: 1085-1090.
Eizaguirre C*, Lenz TL*, Kalbe M, Milinski M (2012) Divergent selection on locally adapted MHC immune genes experimentally proven in the field. Ecology Letters 15: 723-731.
Lenz TL (2011) Computational prediction of MHC II-antigen binding supports divergent allele advantage and explains trans-species polymorphism. Evolution 65: 2380-2390.
