ENTRY EC 4.2.2.7
NAME Heparin lyase
Heparin eliminase
Heparinase
CLASS Lyases
Carbon-oxygen lyases
Acting on polysaccharides
SYSNAME Heparin lyase
REACTION Eliminative cleavage of polysaccharides containing 1,4-linked
D-glucuronate or L-iduronate residues and 1,4-alpha-linked
2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give
oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl
groups at their non-reducing ends.
SUBSTRATE Heparin
DBLINKS University of Geneva ENZYME DATA BANK: 4.2.2.7
WIT (What Is There) Metabolic Reconstruction: 4.2.2.7
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