ENTRY       EC 2.4.99.9
NAME        Lactosylceramide alpha-2,3-sialyltransferase
CLASS       Transferases
            Glycosyltransferases
            Transferring other glycosyl groups
SYSNAME     CMP-N-acetylneuraminate:lactosylceramide
            $ alpha-2,3-N-acetylneuraminyltransferase
REACTION    CMP-N-acetylneuraminate + beta-D-Galactosyl-1,4-beta-D-
            $glucosylceramide = CMP + alpha-N-Acetylneuraminyl-2,3-beta-D-
            $galactosyl-1,4-beta-D-glucosylceramide
SUBSTRATE   CMP-N-acetylneuraminate
            beta-D-Galactosyl-1,4-beta-D-glucosylceramide
PRODUCT     CMP
            alpha-N-Acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-
            $glucosylceramide
COMMENT     Lactose cannot act as acceptor.
PATHWAY     PATH: MAP00600  Sphingoglycolipid metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 2.4.99.9
            WIT (What Is There) Metabolic Reconstruction: 2.4.99.9
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