ENTRY       EC 2.4.1.69
NAME        Galactoside 2-L-fucosyltransferase
            Blood group H alpha-2-fucosyltransferase
CLASS       Transferases
            Glycosyltransferases
            Hexosyltransferases
SYSNAME     GDP-L-fucose:beta-D-galactosyl-R 2-fucosyltransferase
REACTION    GDP-L-fucose + beta-D-galactosyl-R = GDP +
            alpha-L-Fucosyl-1,2-beta-D-galactosyl-R
SUBSTRATE   GDP-L-fucose
            beta-D-galactosyl-R
            Lactose
PRODUCT     GDP
            alpha-L-Fucosyl-1,2-beta-D-galactosyl-R
COMMENT     Lactose can act as acceptor. The action on glycolipid was
            previously listed as EC 2.4.1.89. (cf. EC 2.4.1.65 and 2.4.1.152)
DISEASE     MIM: 182100  Fucosyltransferase-2 (secretor)
            MIM: 211100  Fucosyltransferase-1 (Bombay phenotype)
GENES       HSA: FUT1
DBLINKS     University of Geneva ENZYME DATA BANK: 2.4.1.69
            WIT (What Is There) Metabolic Reconstruction: 2.4.1.69
///