ENTRY       EC 2.3.1.5
NAME        Arylamine N-acetyltransferase
            Arylamine acetylase
CLASS       Transferases
            Acyltransferases
            Acyltransferases
SYSNAME     Acetyl-CoA:arylamine N-acetyltransferase
REACTION    Acetyl-CoA + Arylamine = CoA + N-Acetylarylamine
SUBSTRATE   Acetyl-CoA
            Arylamine
            Aromatic amine
            Serotonin
PRODUCT     CoA
            N-Acetylarylamine
            N-Acetylserotonin
COMMENT     Wide specificity for aromatic amines, including serotonin;
            also catalyses acetyl-transfer between arylamines without CoA.
DISEASE     MIM: 108345  Arylamine N-acetyltransferase-1
            MIM: 243400  Arylamine N-acetyltransferase-2
GENES       HSA: AAC1(NAT1) AAC2(NAT2)
DBLINKS     University of Geneva ENZYME DATA BANK: 2.3.1.5
            WIT (What Is There) Metabolic Reconstruction: 2.3.1.5
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