ENTRY       EC 1.1.99.28
NAME        Clucose-Fructose oxidoreductase
CLASS       Oxidoreductases
            Acting on the CH-OH group of donors
            With other acceptors
REACTION    D-Glucose + D-Fructose = D-Gluconolactone + D-Sorbitol
SUBSTRATE   D-Glucose
            D-Fructose
PRODUCT     D-Gluconolactone
            D-Sorbitol
COMMENT     Mannose, Xylose, Galactose, 2-Deoxyglucose and L-Arabinose
            will function as aldosugar substrates, but with low affinities.
            The ketosugar substrate must be in the open-chain form.
            The apparent affinity for Fructose is low owing to the small
            fraction present in the open-chain form.
            Xylulose and Glycerone will replace but they are poor substrates.
            The enzyme from Z.Mobilis contains tightly-bound NADP.
STRUCTURES  PDB: 1OFG  
DBLINKS     University of Geneva ENZYME DATA BANK: 1.1.99.28
            WIT (What Is There) Metabolic Reconstruction: 1.1.99.28
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