ENTRY       EC 1.1.1.209
NAME        3(or 17)alpha-Hydroxysteroid dehydrogenase
CLASS       Oxidoreductases
            Acting on the CH-OH group of donors
            With NAD+ or NADP+ as acceptor
SYSNAME     3(or 17)alpha-Hydroxysteroid:NAD(P)+ oxidoreductase
REACTION    Androsterone + NAD+ or NADP+ = 5alpha-Androstane-3,17-dione +
            NADH or NADPH
SUBSTRATE   Androsterone
            NAD+
            NADP+
PRODUCT     5alpha-Androstane-3,17-dione
            NADH
            NADPH
COMMENT     Acts on the 3alpha-hydroxyl group of androgens of the
            5alpha-androstane series; and also, more slowly, on the
            17alpha-hydroxyl group of both androgenic and estrogenic
            substrates (cf. EC 1.1.1.51).
DBLINKS     University of Geneva ENZYME DATA BANK: 1.1.1.209
            WIT (What Is There) Metabolic Reconstruction: 1.1.1.209
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