ENTRY       EC 1.1.1.2
NAME        Alcohol dehydrogenase(NADP+)
            Aldehyde reductase(NADPH)
CLASS       Oxidoreductases
            Acting on the CH-OH group of donors
            With NAD+ or NADP+ as acceptor
SYSNAME     Alcohol:NADP+ oxidoreductase
REACTION    Alcohol + NADP+ = Aldehyde + NADPH
SUBSTRATE   NADP+
            Primary alcohol
            Secondary alcohol
PRODUCT     Aldehyde
            NADPH
COFACTOR    Zinc
COMMENT     A zinc protein. Some members of this group oxidize only primary
            alcohols; others act also on secondary alcohols. May be identical
            with EC 1.1.1.19, 1.1.1.33 and 1.1.1.55. A-specific with respect
            to NADPH.
PATHWAY     PATH: MAP00010  Glycolysis / Gluconeogenesis
            PATH: MAP00040  Pentose and glucuronate interconversions
            PATH: MAP00561  Glycerolipid metabolism
MOTIF       PS: PS00059  G-H-E-x(2)-G-x(5)-[GA]-x(2)-[IVAC]
            PS: PS00062  [LIVMFY]-x(9)-[KREQ]-x-[LIVM]-G-[LIVM]-[SC]-N-[FY]
            PS: PS00063  [LIVM]-[PAIV]-[KR]-[ST]-x(4)-R-x(2)-[GSTAEQK]-[NSL]-
                         x(2)-[LIVMFA]
            PS: PS00798  G-[FY]-R-[HAL]-[LIVMF]-D-[STAGC]-[AS]-x(5)-E-x(2)-
                         [LIVM]-G
GENES       BSU: adhA
            MPN: H03_orf351(adh)
            SYN: slr0942
STRUCTURES  PDB: 2ALR  1PED  
DBLINKS     University of Geneva ENZYME DATA BANK: 1.1.1.2
            WIT (What Is There) Metabolic Reconstruction: 1.1.1.2
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